1. preparation

First

Install PyQt5

pip3 install PyQt5

Then create the directory

Create a new folder to store items
The folder example structure is as follows:

/main #Home Folder Name Customization
├─main.pyw #Main startup program
├─conf.py #Used for custom menu configuration
├─/icons  #Used to store icon folders
└─/scripts #Used to store script folders can be omitted

2. code

2.1. Let's create a notification bar to display:

##############
## main.pyw ##
##############
from PyQt5.QtWidgets import QDialog, QSystemTrayIcon, QMenu ,QAction,QApplication
from PyQt5.QtGui import QIcon
import sys


class main(QDialog):
    def __init__(self):
        super().__init__()
        self.loadMenu()
        self.initUI()

    def loadMenu(self):
        menuItems = []  # Menu list
        menuItems.append({"text": "start-up", "icon": "./icons/set.png", "event": self.show, "hot": "D"})
        menuItems.append({"text": "Sign out", "icon": "./icons/close.png", "event": self.close, "hot": "Q"})
        self.trayIconMenu = QMenu(self)# create menu
        #Traverse the text, icons, hotkeys, and click events displayed by the bindings
        #Hotkeys may not work. I just want to show the effect here.
        for i in menuItems: 
            tmp = QAction(QIcon(i["icon"]), i["text"],self, triggered=i["event"])
            tmp.setShortcut(self.tr(i["hot"]))
            self.trayIconMenu.addAction(tmp) 

    def initUI(self):
        self.trayIcon = QSystemTrayIcon(self)  # <=== Create notification bar tray icon
        self.trayIcon.setIcon(QIcon("./icons/menu2.png"))#<=== Set tray icon
        self.trayIcon.setContextMenu(self.trayIconMenu)#<==== Create a right-click connection menu
        self.trayIcon.show()#<====== Display tray
        self.setWindowIcon(QIcon("./icons/menu2.png"))  #<=== Set the form icon
        self.setGeometry(300, 300, 180, 300)  # <=== Set the opening position and width of the form
        self.setWindowTitle('Text')
        # self.show()#<===== Display Form
        # self.hide()#<===== Hide Form
        # Forms are not displayed by default        

    # Rewrite the form closure event to hide when it clicks close
    def closeEvent(self, event):
        if self.trayIcon.isVisible():
            self.trayIcon.hide()


if __name__ == '__main__':
    app = QApplication(sys.argv)
    ex = main()
    sys.exit(app.exec_())

Effect:

2.2. If the notification bar displays successfully, the next configuration is very simple, just bind the display and events.

##############
## conf.pyw ##
##############
import os
import time

def PrScrn():#Call the dll example
    time.sleep(0.5)
    os.popen('rundll32 .\\script\\screenshot\\PrScrn.dll PrScrn')

def Open360Wifi():#Open an application example
    os.popen('"C:\\Program Files (x86)\\360\\360AP\\360AP.exe" /menufree')

def OpenRegedit():#Call command example
    os.popen('regedit')

def Ifconfig():
    os.system('''ipconfig & pause''')

menuItems=[
    #... Examples....
    {"text":"screenshot","icon":"./icons/cut.png","event":PrScrn,"hot":"Alt+P"},
    {"text":"360Wifi","icon":"./icons/wifi.png","event":Open360Wifi,"hot":"Alt+W"},
    {"text":"registry","icon":"./icons/regedit.png","event":OpenRegedit,"hot":"Alt+R"},
    {"text":"ifconfig","icon":"./icons/ip.png","event":Ifconfig,"hot":"Alt+R"}
] 

2.3. Read configuration and display
Reading is very simple:

from PyQt5.QtWidgets import QDialog, QSystemTrayIcon, QMenu ,QAction,QApplication
from PyQt5.QtGui import QIcon
import sys
import conf#<===== Import conf

class main(QDialog):
    def __init__(self):
        super().__init__()
        self.loadMenu()
        self.initUI()

    def loadMenu(self):
        menuItems =conf.menuItems #<========= menu list
        #... slightly.
   
    #... slightly.


if __name__ == '__main__':
    app = QApplication(sys.argv)
    ex = main()
    sys.exit(app.exec_())

2.4. Use Forms
Let me give you a simple example:

from PyQt5.QtWidgets import QDialog, QAction, QApplication, QListWidget, QVBoxLayout, QSystemTrayIcon, QMenu, QListWidgetItem
from PyQt5.QtGui import QIcon
import sys
import conf


class main(QDialog):
    def __init__(self):
        super().__init__()
        self.loadMenu()
        self.initUI()
    #Omit...
    def loadList(self):
        lv = QListWidget()
        for i in range(len(conf.menuItems)):
            itm = conf.menuItems[i]
            if not 'icon' in itm.keys():
                itm["icon"] = None
            if not 'event' in itm.keys():
                itm["event"] = self.show
            if not 'hot' in itm.keys():
                itm["hot"] = 'None' 
            qlv = QListWidgetItem(QIcon(itm["icon"]), self.tr(itm["text"]+"  ("+itm["hot"]+")"))
            qlv.event = itm["event"] 
            # qlv.clicked.connect(self.close)
            lv.insertItem(i + 1, qlv)
        lv.itemDoubleClicked.connect(self.dbclickItem)
        self.layout.addWidget(lv)

    def dbclickItem(self, item):
        item.event()
   #Omit...
 #Omit...

Effect: